How to Use Tretinoin Cream (Australian Guide for Best Results)

Tretinoin is one of the most powerful skincare ingredients available, proven to treat acne, improve texture, reduce pigmentation, and smooth fine lines. But using it correctly is essential to avoid irritation and get the best results.

Follow this guide to apply Tretinoin safely and effectively, especially if you’re just starting out.

✅ What is Tretinoin?

Tretinoin (also known as Retinoic Acid) is a Vitamin A derivative that speeds up skin cell turnover. It’s commonly prescribed for:

  • Acne & breakouts
  • Hyperpigmentation & dark spots
  • Fine lines & wrinkles
  • Uneven skin tone and texture

⚠️ Important Before You Start

  • Expect some initial irritation (dryness, redness, peeling), this is normal and usually temporary.
  • Be patient, it can take 8 to 12 weeks to start seeing visible improvements.

🧴 Step-by-Step: How to Apply Tretinoin Cream

Step 1: Start at Night Only

Tretinoin should be used only at night as it increases your skin's sensitivity to sunlight.

Step 2: Cleanse Your Face Gently

Wash your face with a gentle cleanser and pat it completely dry. Wait 15–20 minutes after washing, applying tretinoin to damp skin increases the chance of irritation.

Step 3: Apply a Pea-Sized Amount

Use a pea-sized amount of cream for your entire face.

Apply small dots on your:

  • Forehead
  • Cheeks
  • Chin
  • Nose

Then gently spread evenly, avoiding:

  • Eyes
  • Lips
  • Corners of the nose
  • Do not apply more than directed, more product does not mean better results and may increase irritation.

Step 4: Moisturise (Buffer Method)

To reduce dryness and flaking, apply a moisturiser 10–15 minutes after tretinoin.

Alternative method for sensitive skin:
Apply a layer of moisturiser before and after tretinoin (called the "sandwich method").

Step 5: Use Sunscreen Every Day

Tretinoin increases your skin’s sensitivity to UV rays. Apply a broad-spectrum SPF 30+ sunscreen every morning, even on cloudy days.

Sun exposure without protection can cause more damage and reverse the benefits of tretinoin.

📆 How Often Should You Use It?

If you’re new to tretinoin, start slow:

Week Frequency
1–2 2x per week
3–4 3–4x per week
5+ Nightly (if tolerated)

You may experience a purging phase in the first few weeks — this is normal and temporary. Stick with it!

⚠️ What to Avoid While Using Tretinoin

  • Harsh scrubs or exfoliants (physical or chemical)
  • Benzoyl peroxide (unless advised by your doctor)
  • AHAs or BHAs (unless skin tolerates)
  • Waxing treated areas
  • Other retinoids (unless instructed)

💡 Tips for Best Results

  • Stay consistent — tretinoin works over time.
  • Keep your skincare routine simple and gentle.
  • Use hydrating products like hyaluronic acid or ceramides to support your skin barrier.
  • Avoid switching to stronger concentrations too soon.
  • If irritation is severe, reduce frequency or consult your provider.

⏳ What to Expect (Timeline)

Timeframe What You May Notice
Week 1–2 Redness, dryness, mild irritation (normal adjustment)
Week 3–6 Possible purging (breakouts get worse before better)
Week 6–8 Skin begins adjusting, early texture improvements
Week 8–12 Visible results: fewer breakouts, smoother texture, faded spots
3–6 months Improved firmness, even tone, reduced fine lines

🙋♀️ FAQs

Is Tretinoin safe for all skin types?

Yes, but sensitive or dry skin may need extra moisturising and slower introduction.

Can I use makeup over Tretinoin?

Yes, just make sure your skin is moisturised and your SPF is applied in the morning.

Can I use other actives with Tretinoin?

Not initially. Once your skin builds tolerance, you can slowly reintroduce products like niacinamide, azelaic acid, or vitamin C one at a time.

🧴 Products That Pair Well With Tretinoin

  • Gentle cleanser (no sulfates or fragrance)
  • Fragrance-free moisturiser (ceramides, hyaluronic acid)
  • SPF 30+ sunscreen (broad-spectrum, every day)

🛍️ Where to Get Tretinoin in Australia?

At Tretinoin Store, we offer:

✅ Free online prescription
✅ Fast, discreet delivery Australia-wide
✅ Genuine, dermatologist-approved Tretinoin formulations

👉 Browse Tretinoin Creams